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AETHERIA
TRANSLATIONAL MEDICINE · COMPANION DIAGNOSTICS · AGENTIC AI

Decoding Clinical Precision with Next-Gen Bio-AI.

Aetheria Lab is an independent research & strategy node focused on global regulatory science (FDA / NMPA / EMA), companion diagnostics (CDx) architecture, computational pathology biomarkers, and multi-agent scientific workflows.

PILLAR 01 // GLOBAL CDx STRATEGY

Cross-Regional Regulatory Intelligence

Systematic verification of Prescribing Information (Section 2.1 Patient Selection), PMA records, and PMR/PMC commitments across US FDA, China NMPA, and EU IVDR frameworks.

PILLAR 02 // AI PATHOLOGY & BIOMARKERS

Quantitative Continuous Scoring & ML

Evaluating deep learning whole-slide imaging (WSI) algorithms (e.g., QCS-NMR) and routine clinical-laboratory ensemble models (e.g., SCORPIO) for immunotherapy & ADC stratification.

PILLAR 03 // AGENTIC WORKFLOWS

Zero-Hallucination Context Architecture

Orchestrating long-horizon local memory graphs and multi-model verification pipelines (Gemini + Claude Code) for high-stakes translational decision support.

RECENT BRIEFINGS & TECHNICAL NOTES

UPDATED: Q4 2026
NAT MED 2025 SCORPIO Ensemble Model: Routine Blood & Clinical Features Outperform TMB/PD-L1 in Pan-Cancer ICI
RCOX + FSSVM + RSF | N=9,745
AI-CDx QCS-NMR Computational Pathology in NSCLC (Dato-DXd): Subcellular Membrane/Cytoplasm OD Ratio
Cut-off: ≥75% cells NMR ≤0.56
ESCC RCT Perioperative Immunotherapy Stratification Strategy: PD-L1 CPS ≥10 vs. CPS <10/NE
Confounding Control & Label Defense